Friday, February 27, 2009

Baylis-Hillman Reaction

The formation of a C-C single bond between the alpha-position of conjugated carbonyl compounds, such as esters and amides, and carbon electrophiles, such as aldehydes and activated ketones in the presence of a suitable nucleophilic catalyst, particularly a tertiary amine.

1 comment:

LLK said...

Popular but not a super-useful reaction for synthesis.