Friday, February 27, 2009

Myers Asymmetric Alkylation

The alkylation of N-acylated pseudoephedrines to obtain enantiomerically enriched alpha-alkylated aldehydes, ketones, carboxylic acids, and alcohols.

Total Synthesis of GEX1A
Timothy J. Murray and Craig J. Forsyth
Org. Lett., 2008, 10 (16), pp 3429–3431
DOI: 10.1021/ol800902g

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