Friday, February 27, 2009

Staudinger Reaction

The reaction of organic azides with trivalent phosphorous compounds (e.g., trialkyl- or triarylphosphines) to afford the corresponding aza-ylides.

Enantioselective Synthesis of Marine Indole Alkaloid Hamacanthin B
Biao Jiang, Cai-Guang Yang, and Jun Wang
J. Org. Chem., 2002, 67 (4), pp 1396–1398
DOI: 10.1021/jo0108109

A FRET-Based Fluorogenic Phosphine for Live-Cell Imaging with the Staudinger Ligation
Matthew J. Hangauer and Carolyn R. Bertozzi
Angew. Chem. Int. Ed., 2008, 47 (13), pp 2394-2397
DOI: 10.1002/anie.200704847

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