Friday, February 27, 2009

Finkelstein Reaction

The equilibrium exchange of the halogen atom in alkyl halides for another halogen atom.

Copper-Catalyzed Halogen Exchange in Aryl Halides: An Aromatic Finkelstein Reaction
Artis Klapars and Stephen L. Buchwald
J. Am. Chem. Soc., 2002, 124 (50), pp 14844–14845
DOI: 10.1021/ja028865v

A novel approach for the synthesis of the peripheral benzodiazepine receptor ligand, PK11195
Louise Stevenson, Sally L. Pimlott and Andrew Sutherland
Tetrahedron Lett., 2007, 48 (40), pp 7137-7139
DOI: 10.1016/j.tetlet.2007.07.203

(From July 4, 2008)

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