Friday, February 27, 2009

Weinreb Ketone Synthesis

The synthesis of ketones from N-methoxy-N-methylamides (Weinreb's amides) with organometallic reagents.

Formal Total Synthesis of RK-397 via an Asymmetric Hydration and Iterative Allylation Strategy
Haibing Guo, Matthew S. Mortensen and George A. O’Doherty
Org. Lett., 2008, 10 (14), pp 3149–3152
DOI: 10.1021/ol801055b

(From 09/05/08)

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